The Best Glutamine on the Market That Will Relieve Muscular Pain

If you are training intensely, you know what muscle pain means best. Glutamine is the most helpful supplement when these pains are intense and you need to train frequently. Do you know why?

Glutamine is very beneficial for the body in two ways. If you are dealing with muscle building, enhancing the muscle growth effect of leucine; Storing enough glycogen, even if you're on a low-carb diet to speed up muscle repair. These two important benefits of glutamine help you achieve faster muscle development with less muscle pain and fatigue.

The Function of Glutamine in the Body

Glutamine is an important amino acid for the immune system. It is essential for immune cells, white blood cells and some tissues.Some studies show that glutamine supplements can improve the immune system and reduce infections.

It is also thought that glutamine can improve the health of the intestinal system. It is stated that glutamine can protect the body against permeable bowel syndrome.

Glutamine provides protein synthesis and breakdown like other alpha-amino acids. However, there is much more than that. Glutamine is involved in BCAA metabolism, intestinal wall maintenance, normal immune function, glucose formation, water conduction, inter-nervous conduction etc. significantly affects situations.

Your kidneys are the main user of glutamine, and ammonia, separated from glutamine, works to maintain your body's acid-base balance. Wherever there is ammonia, there is also glutamine. For example, as metabolic acidosis increases due to intense exercise or protein-rich diet, glutamine use of kidneys increases.

A study found that a diet of only 4 days of protein and fat was sufficient to cause a 25% reduction in plasma and muscle tissue glutamine levels. signs of glutamine deficiency are seen.

Effect of Glutamine on Performance

A clinical study found that glutamine, which is taken as a supplement when athletes suffer from thirst, increased exercise performance, and when combined with drinks containing glucose and electrolyte, water and electrolyte absorption increased. Externally, glutamine supplements have also been shown to increase growth hormone levels as a response to fatigue.

Extracellular glutamine concentrations have been shown to activate the mTOR signal, which is responsible for increasing muscle size. However, the benefit of glutamine supplements depends on meeting some other conditions: the mTOR signal needs the presence of BCAA (leucine) as well as the cellular watering level.

In another case, athletes who received creatine loading for 8 weeks and also used 4 grams of glutamine every day saw more increases in muscle mass than those who used only creatine. This may seem important, but it is difficult to report on such a low dose in just 8 weeks. An estimate may be made that a higher dose or a longer run will result in significant differences.

Differences of Glutamine Types

The most important thing to consider when choosing a glutamine product is in what way. If you are taking powder, capsules or tablets, L-glutamine in free form is best. However, since glutamine is degradable, avoid instant drinks or protein bars that claim to contain L-glutamine.

If you prefer instant beverages and bars, look for peptide-bound forms of glutamine, such as L-alanyl-L-glutamine, glycyl-L-glutamine hydrate or products containing "glutamine peptide". The glutamine concentration in these peptide forms is about 65-70%. That is, every 10 g of glutamine peptide 6.5-7 g. Contains glutamine. It is necessary to adjust the dose accordingly.

Regardless of its form, up to 90% of the glutamine taken is eliminated in the first pass. A very small portion of the consumed glutamine will go beyond the liver. A large part of glutamine is eliminated by digestive enterocytes and immune cells in the intestines.

It is best to avoid using products that contain N-acetyl-1-glutamine (not to be mixed with N-acetyl glucosamine) or alpha-ketoisocoproil glutamine (also known as aKIC-glutamine). Both forms are not degradable, but they are forms where very little of glutamine can be used.

Products That Can Be Used With Glutamine

Let's assume that glutamine is used with sodium and other electrolytes. The transport of glutamine occurs via the sodium-dependent mechanism and has been shown to increase cell volume, electrolyte absorption and water delivery. This can be beneficial for both endurance and physics. Significant reductions in cell water may interfere with the mTOR signal required for muscle building. Glutamine can increase cell volume, electrolyte absorption and hydration. This can be beneficial for endurance and physics. Other supports that can be used with glutamine can be listed as follows:

1. BCAA
By combining BCAA and glutamine, there are two main reasons why more gains in muscle mass and performance are achieved. First, ammonia density, and hence glutamine, directly affect BCAA metabolism. Second, the mTOR signal from extracellular glutamine needs BCAA (especially leucine) first. BCAA + Glutamine improves performance and muscle building.

2. Citrulline
Glutamine leads the synthesis of arginine and NO by carrying citrulline between tissues. Using glutamine with citrulline increases the ability of citrulline to trigger nitric oxide production, which allows better oxygen and build-up to be delivered to the skeletal muscle. The fact that more building materials go to the muscles means faster recovery and growth. Although it does not appear directly, glutamine has a finger in many processes.

3. Alpha-Ketoglutarate
Like glutamine, aKG leads to glutamate, dose-dependent empty glutamine reduction and an increase in the mTOR signal. This means that when taken with glutamine aKG, it increases muscle growth potential and glutathione production, a powerful antioxidant.

4. Glucose or N-Acetylglucosamine
Glucose deprivation reduces glutamine absorption and negatively affects cell growth and life. If you are on a low-carb diet, supplemented glycoprotein N-acetylglucosamine (NAG) can restore glutamine absorption and metabolism, potentially improving healing and cell function.

How to Use it?

It seems that daily glutamine supplements should be high to increase glutamine density at the plasma level; at least 20-30 g daily, provided that it is taken frequently.

For deeper examination, people who are seriously ill usually take 20-30 grams intravenously daily. Let's think you take glutamine. The glutamine they take is 100%. If glutamine is taken orally, this ratio will not be more than 30%. Therefore, it is recommended to use up to 30 g glutamine in divided doses spread throughout the day, preferably with a meal or a carbohydrate snack, to support the use of glucose.

During training days, glutamine should be used before or during exercise to support water and electrolyte delivery and BCAA metabolism. 10 gr before, during and after the training. you can take glutamine. If you are going to exercise later and use glutamine, you can reduce these doses to 5g. Days when you are not training, at least 5 g every 2-3 hours to maintain the glutamine concentration in the plasma. You should use glutamine. There is no need to use glutamine for a long time. During periods of intense physical pressure, it is necessary to support the need for glutamine.